This program generates Simon's optimal two-stage designs (Simon, 1989) and admissible designs from Jung et al. (2004) for Phase II single arm clincial trials.
1. Simon R (1989). Controlled Clinical Trials 10: 1-10.
Click here to download Simon's (1989) article.
2. Jung SH, Lee TY, Kim KM, George S (2004). Admissible two-stage designs for phase II cancer clinical trials, Statistics in Medicine 23: 561-569.