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Number	Datatype	Title	LEAD AUTHOR	CO-AUTHOR	Final Proposals/Manuscripts
B1		Concurrent validity of the Alcohol Use Disorders Identification Test (AUDIT) and AUDIT zones in defining levels of severity among out-patients with alcohol dependence in the COMBINE study.	Donovan, Dennis Donovan, Dennis Doyle, Suzanne Greenfield, Shelly Kivlahan, Dan Longabaugh, Richard	Doyle, Suzanne Greenfield, Shelly Kivlahan, Dan Longabaugh, Richard
B11		Psychometrics of the Drinker Inventory of Consequences (DrInC).	Forcehimes, Alyssa Forcehimes, Alyssa Baer, John Kenna, George Miller, William Tonigan, Scott	Baer, John Kenna, George Miller, William Tonigan, Scott
B12		Further validation of the alcohol dependence scale as an index of severity.	Saxon, Andrew Saxon, Andrew Doyle, Suzanne Kivlahan, Dan	Doyle, Suzanne Kivlahan, Dan
B12A1		A validation study of the alcohol dependence scale.	Doyle, Suzanne Doyle, Suzanne Donovan, Dennis	Donovan, Dennis
B14		Readiness to change.	DiClimente, Carlo DiClimente, Carlo Donovan, Dennis Doyle, Suzanne	Donovan, Dennis Doyle, Suzanne
B1a1		The factor structure of the Alcohol Use Disorders Identification Test (AUDIT).	Doyle, Suzanne Doyle, Suzanne Donovan, Dennis Kivlahan, Dan	Donovan, Dennis Kivlahan, Dan
B21		Factors affecting %CDT status at entry into a multisite clinical treatment trial: experience from the COMBINE study.	Anton, Raymond Anton, Raymond Youngblood, Marston	Youngblood, Marston
B23		Measuring economic outcomes of alcohol treatment using the economic form 90.	Bray, Jeremy Bray, Jeremy Cisler, Ron Couper, DJ Kivlahan, Dan Martin, Daniel Miller, William Mitra, Debanjali Zarkin, Gary	Cisler, Ron Couper, DJ Kivlahan, Dan Martin, Daniel Miller, William Mitra, Debanjali Zarkin, Gary
B3		Gender differences related to age and ethnicity in a multi-site alcohol clinical trial.	Greenfield, Shelly Greenfield, Shelly Garbutt, James Mason, Barbara Pettinati, Helen Randall, Carrie Youngblood, Marston	Garbutt, James Mason, Barbara Pettinati, Helen Randall, Carrie Youngblood, Marston
B5		Characteristics of first-time alcohol treatment seekers: The COMBINE study.	LoCastro, Joseph LoCastro, Joseph Couper, DJ Donovan, Dennis Pope, Kimberly W. Potter, Jennifer	Couper, DJ Donovan, Dennis Pope, Kimberly W. Potter, Jennifer	PMCID: PMC2583384
CM1		Do patients with alcohol dependence respond to placebo? Results from the COMBINE study.	Weiss, Roger Weiss, Roger Hosking, James LoCastro, Joseph O'Malley, Stephanie Swift, Robert	Hosking, James LoCastro, Joseph O'Malley, Stephanie Swift, Robert	PMCID: PMC2575123
CM11		An intervention for treating alcohol dependence: relating elements of medical management to patient outcomes with implications for primary care.	Ernst, Denise Ernst, Denise Donovan, Dennis Longabaugh, Richard Pettinati, Helen Weiss, Roger	Donovan, Dennis Longabaugh, Richard Pettinati, Helen Weiss, Roger	PMCID: PMC2532776
Number	Datatype	Title	LEAD AUTHOR	CO-AUTHOR	Final Proposals/Manuscripts
CM16		Cost and cost-effectiveness of the COMBINE study for alcohol-dependent patients.	Zarkin, Gary Zarkin, Gary Aldridge, Arnie Bray, Jeremy Cisler, Ron Couper, DJ Mitra, Debanjali	Aldridge, Arnie Bray, Jeremy Cisler, Ron Couper, DJ Mitra, Debanjali
CM18		OPRM1 Asn40Asp predicts response to naltrexone treatment: a haplotype-based approach.	Oroszi, Gabor Oroszi, Gabor Anton, Raymond Couper, DJ Goldman, David O'Malley, Stephanie Pettinati, Helen Swift, Robert Yuan,	Anton, Raymond Couper, DJ Goldman, David O'Malley, Stephanie Pettinati, Helen Swift, Robert Yuan,	PMCID: PMC2679376
CM2		Alcohol treatment effects on secondary non-drinking outcomes and quality of life: The COMBINE study.	LoCastro, Joseph LoCastro, Joseph Anton, Raymond Cisler, Ron Donovan, Dennis Mattson, Margaret Youngblood, Marston Zweben, A	Anton, Raymond Cisler, Ron Donovan, Dennis Mattson, Margaret Youngblood, Marston Zweben, A	PMCID: PMC2653605
CM3		Relationship between medication adherence and treatment outcomes: The COMBINE study.	Zweben, A Zweben, A Ciraulo, Domenic Cox, Gorroochurn, Mattson, Margaret Pettinati, Helen Weiss, Roger Youngblood, Marston	Ciraulo, Domenic Cox, Gorroochurn, Mattson, Margaret Pettinati, Helen Weiss, Roger Youngblood, Marston	PMCID: PMC2574640
CM6		Predictors of Treatment Outcomes - WAVE C	Donovan, Dennis Donovan, Dennis Anton, Raymond Johnson, Bankole LoCastro, Joseph Mason, Barbara Pettinati, Helen Zweben, A	Anton, Raymond Johnson, Bankole LoCastro, Joseph Mason, Barbara Pettinati, Helen Zweben, A
CM8		An evaluation of mu-opioid receptor (OPRM1) as a predictor of naltrexone response in the treatment of alcohol dependence: Results from the COMBINE study.	Anton, Raymond Anton, Raymond Couper, DJ Goldman, David O'Malley, Stephanie Oroszi, Gabor Pettinati, Helen Swift, Robert	Couper, DJ Goldman, David O'Malley, Stephanie Oroszi, Gabor Pettinati, Helen Swift, Robert	PMCID: PMC2666924
CP1		Testing combined pharmacotherapies and behavioral interventions for alcohol dependence (the COMBINE study): A pilot feasibility study.	Anton, Raymond Anton, Raymond Ait-Daoud, Nassima Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Flannery, Barbara Garbutt, James Gastfriend, David Greenfield, Shelly Hosking, James Johnson, Bankole Kivlahan, Dan Krystal, John Latham, Patricia LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Petrakis, Ismene Pettinati, Helen Randall, Carrie Roache, John Salvato, Fernando Saxon, Andrew Swift, Robert Tonigan, Scott Weiss, Roger Westerberg, Verner Williams, Lauren Zweben, A	Ait-Daoud, Nassima Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Flannery, Barbara Garbutt, James Gastfriend, David Greenfield, Shelly Hosking, James Johnson, Bankole Kivlahan, Dan Krystal, John Latham, Patricia LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Petrakis, Ismene Pettinati, Helen Randall, Carrie Roache, John Salvato, Fernando Saxon, Andrew Swift, Robert Tonigan, Scott Weiss, Roger Westerberg, Verner Williams, Lauren Zweben, A
CP2		Testing combined pharmacotherapies and behavioral interventions in alcohol dependence: Rationale and methods.	Gastfriend, David Gastfriend, David Ait-Daoud, Nassima Anton, Raymond Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Flannery, Barbara Garbutt, James Gastfriend, David Greenfield, Shelly Hosking, James Johnson, Bankole Kivlahan, Dan Krystal, John Latham, Patricia LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Petrakis, Ismene Pettinati, Helen Randall, Carrie Roache, John Salvato, Fernando Saxon, Andrew Swift, Robert Tonigan, Scott Weiss, Roger Westerberg, Verner Williams, Lauren Zweben, A	Ait-Daoud, Nassima Anton, Raymond Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Flannery, Barbara Garbutt, James Gastfriend, David Greenfield, Shelly Hosking, James Johnson, Bankole Kivlahan, Dan Krystal, John Latham, Patricia LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Petrakis, Ismene Pettinati, Helen Randall, Carrie Roache, John Salvato, Fernando Saxon, Andrew Swift, Robert Tonigan, Scott Weiss, Roger Westerberg, Verner Williams, Lauren Zweben, A
CP3		Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.	Anton, Raymond Anton, Raymond Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Gastfriend, David Hosking, James Johnson, Bankole LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Pettinati, Helen Randall, Carrie Swift, Robert Weiss, Roger Williams, Lauren Zweben, A	Ciraulo, Domenic Cisler, Ron Couper, DJ Donovan, Dennis Gastfriend, David Hosking, James Johnson, Bankole LoCastro, Joseph Longabaugh, Richard Mason, Barbara Mattson, Margaret Miller, William O'Malley, Stephanie Pettinati, Helen Randall, Carrie Swift, Robert Weiss, Roger Williams, Lauren Zweben, A
CP4		Combined pharmacotherapies and behavioral interventions for alcohol dependence (the COMBINE) study: Examination of posttreatment drinking outcomes.	Donovan, Dennis Donovan, Dennis Anton, Raymond Hosking, James Longabaugh, Richard Miller, William Youngblood, Marston	Anton, Raymond Hosking, James Longabaugh, Richard Miller, William Youngblood, Marston
M0		Overview of COMBINE	Mattson, Margaret Mattson, Margaret Litten, Raye	Litten, Raye
M1		When worlds collide: blending the divergent traditions of pharmacotherapy and psychotherapy outcome research.	Miller, William Miller, William LoCastro, Joseph Longabaugh, Richard O'Malley, Stephanie Zweben, A	LoCastro, Joseph Longabaugh, Richard O'Malley, Stephanie Zweben, A
Number	Datatype	Title	LEAD AUTHOR	CO-AUTHOR	Final Proposals/Manuscripts
M10		Developing a baseline assessment battery: Balancing patient time burden with essential clinical and research monitoring.	Gastfriend, David Gastfriend, David Donovan, Dennis Lefebvre, Rachel Murray, Kelly	Donovan, Dennis Lefebvre, Rachel Murray, Kelly
M11		Measurement and choice of drinking outcome variables in the COMBINE study.	Anton, Raymond Anton, Raymond Randall, Carrie	Randall, Carrie
M12		Assessing non-drinking outcomes in combined pharmacotherapy and psychotherapy clinical trials for the treatment of alcohol dependence.	Cisler, Ron Cisler, Ron Donovan, Dennis Kivlahan, Dan Mattson, Margaret	Donovan, Dennis Kivlahan, Dan Mattson, Margaret
M13		Quality of life as an outcome measure in alcoholism treatment research.	Donovan, Dennis Donovan, Dennis Cisler, Ron Longabaugh, Richard Mattson, Margaret Zweben, A	Cisler, Ron Longabaugh, Richard Mattson, Margaret Zweben, A
M14		Choosing pharmacotherapies for the COMBINE study - process and procedures: an investigational approach to combination pharmacotherapy for the treatment of alcohol dependence.	Swift, Robert Swift, Robert Pettinati, Helen	Pettinati, Helen
M15		Rationale for combining acamprosate and naltrexone for treating alcohol dependence.	Mason, Barbara
M16		The COMBINE SAFTEE: a structured instrument for collecting adverse events adapted for clinical studies in the alcoholism field.	Johnson, Bankole Johnson, Bankole Ait-Daoud, Nassima Roache, John	Ait-Daoud, Nassima Roache, John
M17		A structured approach to medical management: a psychosocial intervention to support pharmacotherapy in the treatment of alcohol dependence.	Pettinati, Helen Pettinati, Helen Donovan, Dennis Dundon, Bill Ernst, Denise Miller, William Rounsaville, Bruce Weiss, Roger	Donovan, Dennis Dundon, Bill Ernst, Denise Miller, William Rounsaville, Bruce Weiss, Roger
M18		Origins, issues and options in the development of the combined behavioral intervention.	Longabaugh, Richard Longabaugh, Richard LoCastro, Joseph Miller, William Zweben, A	LoCastro, Joseph Miller, William Zweben, A
M19		Training, supervision and quality monitoring of the COMBINE study behavioral interventions.	Miller, William Miller, William Arciniega, Lisa Ernst, Denise Forcehimes, Alyssa Moyers, Theresa	Arciniega, Lisa Ernst, Denise Forcehimes, Alyssa Moyers, Theresa
M2		Factorial designs in clinical trials: options for combination treatment studies.	Couper, DJ Couper, DJ Cisler, Ron Gastfriend, David Hosking, James Kivlahan, Dan	Cisler, Ron Gastfriend, David Hosking, James Kivlahan, Dan
M3		Design and analysis of trials of combination therapies.	Hosking, James Hosking, James Anton, Raymond Cisler, Ron Couper, DJ Gastfriend, David Kivlahan, Dan	Anton, Raymond Cisler, Ron Couper, DJ Gastfriend, David Kivlahan, Dan
Number	Datatype	Title	LEAD AUTHOR	CO-AUTHOR	Final Proposals/Manuscripts
M4		Use of a "psychotherapy with no pills" treatment condition as part of a combined pharmacotherapy-psychotherapy research study of alcohol dependence	Weiss, Roger Weiss, Roger Hosking, James LoCastro, Joseph Longabaugh, Richard Miller, William Swift, Robert Zweben, A	Hosking, James LoCastro, Joseph Longabaugh, Richard Miller, William Swift, Robert Zweben, A
M5		Cost methodology of COMBINE.	Zarkin, Gary Zarkin, Gary Bray, Jeremy Cisler, Ron Kivlahan, Dan Mitra, Debanjali	Bray, Jeremy Cisler, Ron Kivlahan, Dan Mitra, Debanjali
M7		How pilot studies improve large-scale clinical trials: lessons learned from the COMBINE study.	O'Malley, Stephanie O'Malley, Stephanie Hosking, James Martin, Daniel Mason, Barbara	Hosking, James Martin, Daniel Mason, Barbara
M8		Recruiting and retaining participants in a combined behavioral and pharmacological clinical trial.	Zweben, A Zweben, A Barrett, D Berger, Lisa Murray, Kelly	Barrett, D Berger, Lisa Murray, Kelly
M9		Coordinating and monitoring multisite clinical trials that combine pharmacological and behavioral treatments.	Youngblood, Marston Youngblood, Marston Devine, Eric Hubatch, S Latham, Patricia Murray, Kelly	Devine, Eric Hubatch, S Latham, Patricia Murray, Kelly
O13		Effects of alcoholism typology on response to naltrexone in the COMBINE study.	Bogenschutz, Michael Bogenschutz, Michael Pettinati, Helen Tonigan, Scott	Pettinati, Helen Tonigan, Scott	PMCID: PMC2626136
O15		Effects on health care use	Bray, Jeremy Bray, Jeremy Aldridge, Arnie Morgan-Lopez, Antonio Zarkin, Gary	Aldridge, Arnie Morgan-Lopez, Antonio Zarkin, Gary
O16		Blood pressure reduction during treatment for alcohol dependence: Results from the Combining Medications and Behavioral Interventions for Alcoholism (COMBINE) study.	Stewart, Scott H. Stewart, Scott H. Anton, Raymond Latham, Patricia Miller, Randall,	Anton, Raymond Latham, Patricia Miller, Randall,	PMCID: PMC2634596
O18		COMT genotype influences the effect of alcohol on blood pressure: Results from the COMBINE study.	Stewart, Scott H. Stewart, Scott H. Anton, Raymond Oroszi, Gabor Randall,	Anton, Raymond Oroszi, Gabor Randall,	PMCID: PMC2630169
O7		Validation of a nine-dimensional measure of drinking motives for use in clinical applications: The desired effects of drinking scale.	Doyle, Suzanne Doyle, Suzanne Donovan, Dennis Simpson, Tracy	Donovan, Dennis Simpson, Tracy
O8		The impact of the combined behavioral intervention (CBI) on client drinking outcomes in the COMBINE study.	Moyers, Theresa Moyers, Theresa Arciniega, Lisa Houck, J.M. Longabaugh, Richard Miller, William	Arciniega, Lisa Houck, J.M. Longabaugh, Richard Miller, William