Brain MRI (http://www.cscc.unc.edu/aricmri)
This study is designed to learn more about risk factors related to progression of brain abnormalities and how progression may relate to clinical outcomes such as cognitive decline and stroke. Brain morphology can be readily visualized using magnetic resonance imaging, or MRI, making it possible to detect and quantify changes in the brain's structure and vasculature. However, little is known about what factors influence brain changes and whether those changes have any prognostic significance.
CARe Center (http://www.broad.mit.edu/gen_analysis/care/index.php/Main_Page )
NHLBI’s Candidate-gene Association REsource (CARe) Study will support quite extensive genotyping in up to 50,000 participants from nine NHLBI-supported cohort studies (the CARe Cohorts). This project is expected to produce rapid scientific progress, rich opportunities for investigators, and great benefit to society.
Jackson Heart Study (http://jhs.jsums.edu/jhsinfo)
There is a greater prevalence of cardiovascular disease (CVD) among African Americans. The purpose of the Jackson Heart Study is to explore the reasons for this disparity and to uncover new approaches to reduce it. The Jackson Heart Study (JHS) is the largest single-site, prospective, epidemiologic investigation of CVD that has ever been undertaken. It is a population-based, longitudinal study. The study site is Jackson, Mississippi.
Sleep Heart Health Study (SHHS) (http://www.jhucct.com/shhs/index.asp)
The Sleep Heart Health Study is a multi-center cohort study that has been implemented by the National Heart, Lung, and Blood Institute to determine cardiovascular and other consequences of sleep-disordered breathing. The study was motivated by the increasing recognition of the frequent occurrence of sleep-disordered breathing in the general population and mounting evidence that sleep-disordered breathing may increase risk for cardiovascular diseases, including coronary artery disease and stroke, and for hypertension and may reduce quality of life generally.
